Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant

<p>Abstract</p> <p>Background</p> <p>Optineurin is a multifunctional protein involved in several functions such as vesicular trafficking from the Golgi to the plasma membrane, NF-κB regulation, signal transduction and gene expression. Mutations in optineurin are associa...

Full description

Bibliographic Details
Main Authors: Rangaraj Nandini, Radha Vegesna, Jain Nishant, Chalasani Madhavi L, Nagabhushana Ananthamurthy, Balasubramanian Dorairajan, Swarup Ghanshyam
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/11/4