Nonsteroidal Anti-Inflammatory Drugs and the Kidney
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit the isoenzymes COX-1 and COX-2 of cyclooxygenase (COX). Renal side effects (e.g., kidney function, fluid and urinary electrolyte excretion) vary with the extent of COX-2-COX-1 selectivity and the administered dose of these compounds. While young...
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Format: | Article |
Language: | English |
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MDPI AG
2010-07-01
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Series: | Pharmaceuticals |
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Online Access: | http://www.mdpi.com/1424-8247/3/7/2291/ |