Inverse Association of Circulating SIRT1 and Adiposity: A Study on Underweight, Normal Weight, and Obese Patients

Inverse Association of Circulating SIRT1 and Adiposity: A Study on Underweight, Normal Weight, and Obese Patients

Context: Sirtuins (SIRTs) are NAD+-dependent deacetylases, cellular sensors to detect energy availability, and modulate metabolic processes. SIRT1, the most studied family member, influences a number of tissues including adipose tissue. Expression and activity of SIRT1 reduce with weight gain and in...

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Bibliographic Details
Main Authors: Stefania Mariani, Maria R. di Giorgio, Paolo Martini, Agnese Persichetti, Giuseppe Barbaro, Sabrina Basciani, Savina Contini, Eleonora Poggiogalle, Antonio Sarnicola, Alfredo Genco, Carla Lubrano, Aldo Rosano, Lorenzo M. Donini, Andrea Lenzi, Lucio Gnessi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Endocrinology
Subjects:
sirtuins
circulating SIRT1
adiposity
anorexia
obesity
body fat mass
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00449/full

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https://www.frontiersin.org/article/10.3389/fendo.2018.00449/full

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