Hologram QSAR Studies of Antiprotozoal Activities of Sesquiterpene Lactones

Hologram QSAR Studies of Antiprotozoal Activities of Sesquiterpene Lactones

Infectious diseases such as trypanosomiasis and leishmaniasis are considered neglected tropical diseases due the lack for many years of research and development into new drug treatments besides the high incidence of mortality and the lack of current safe and effective drug therapies. Natural product...

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Bibliographic Details
Main Authors: Gustavo H. G. Trossini, Vinícius G. Maltarollo, Thomas J. Schmidt
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Molecules
Subjects:
HQSAR
sesquiterpene lactones
Trypanosoma brucei
Trypanosoma cruzi
Leishmania donovani
Plasmodium falciparum
antiprotozoal activity
fragment-based drug design
Online Access:http://www.mdpi.com/1420-3049/19/7/10546

Internet

http://www.mdpi.com/1420-3049/19/7/10546

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