The Inflammatory Feed-Forward Loop Triggered by the Complement Component C3 as a Potential Target in Endometriosis

The complement system is a major component of humoral innate immunity, acting as a first line of defense against microbes via opsonization and lysis of pathogens. However, novel roles of the complement system in inflammatory and immunological processes, including in cancer, are emerging. Endometrios...

Full description

Bibliographic Details
Main Authors: Chiara Agostinis, Sonia Zorzet, Andrea Balduit, Gabriella Zito, Alessandro Mangogna, Paolo Macor, Federico Romano, Miriam Toffoli, Beatrice Belmonte, Gaia Morello, Anna Martorana, Violetta Borelli, Giuseppe Ricci, Uday Kishore, Roberta Bulla
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
C3
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.693118/full