Schisandrin B Ameliorates ICV-Infused Amyloid β Induced Oxidative Stress and Neuronal Dysfunction through Inhibiting RAGE/NF-κB/MAPK and Up-Regulating HSP/Beclin Expression.

Amyloid β (Aβ)-induced neurotoxicity is a major pathological mechanism of Alzheimer's disease (AD). Our previous studies have demonstrated that schisandrin B (Sch B), an antioxidant lignan from Schisandra chinensis, could protect mouse brain against scopolamine- and cisplatin-induced neuronal d...

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Main Authors:	Vijayasree V Giridharan, Rajarajan A Thandavarayan, Somasundaram Arumugam, Makoto Mizuno, Hiroyuki Nawa, Kenji Suzuki, Kam M Ko, Prasanna Krishnamurthy, Kenichi Watanabe, Tetsuya Konishi
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4640572?pdf=render

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http://europepmc.org/articles/PMC4640572?pdf=render

Schisandrin B Ameliorates ICV-Infused Amyloid β Induced Oxidative Stress and Neuronal Dysfunction through Inhibiting RAGE/NF-κB/MAPK and Up-Regulating HSP/Beclin Expression.

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