Genotype-Epigenotype Interaction at the IGF2 DMR

Paternally expressed Insulin-like Growth Factor II (IGF2) encodes a gene whose protein product functions as a potent growth mitogen. Overexpression of IGF2 has been implicated in a wide number of disorders and diseases. IGF2 is regulated in part by differential methylation of the two parentally deri...

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Bibliographic Details
Main Authors: Susan K. Murphy, Erin Erginer, Zhiqing Huang, Zachary Visco, Cathrine Hoyo
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Genes
Subjects:
Online Access:http://www.mdpi.com/2073-4425/6/3/777