8-Formylophiopogonanone B Antagonizes Paraquat-Induced Hepatotoxicity by Suppressing Oxidative Stress

8-Formylophiopogonanone B Antagonizes Paraquat-Induced Hepatotoxicity by Suppressing Oxidative Stress

Flavonoids are some of the most important natural products with a variety of physiological activities. 8-Formylophiopogonanone B (8-FOB) is a naturally existing homoisoflavonoid in Ophiopogon japonicus. Paraquat (PQ) has been widely used as a potent herbicide and has high toxicity in humans. The goa...

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Bibliographic Details
Main Authors: Jing-yu Qian, Ping Deng, Yi-dan Liang, Li Pang, Li-chuan Wu, Ling-ling Yang, Zhouv Zhou, Zheng-ping Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Pharmacology
Subjects:
8-formylophiopogonanone B
paraquat
hepatotoxicity
oxidative stress
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01283/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.01283/full

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