Brd4 Regulates the Homeostasis of CD8+ T-Lymphocytes and Their Proliferation in Response to Antigen Stimulation

Brd4 Regulates the Homeostasis of CD8+ T-Lymphocytes and Their Proliferation in Response to Antigen Stimulation

CD8+ T cells are major components of adaptive immunity and confer robust protective cellular immunity, which requires adequate T-cell numbers, targeted migration, and efficient T-cell proliferation. Altered CD8+ T-cell homeostasis and impaired proliferation result in dysfunctional immune response to...

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Bibliographic Details
Main Authors: Zhilin Peng, Yiwen Zhang, Xiancai Ma, Mo Zhou, Shiyu Wu, Zheng Song, Yaochang Yuan, Yingshi Chen, Yuzhuang Li, Guanwen Wang, Feng Huang, Yidan Qiao, Baijing Xia, Weiwei Liu, Jun Liu, Xu Zhang, Xin He, Ting Pan, Hanshi Xu, Hui Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
CD8+ T cell homeostasis
CD8+ T cell proliferation
Brd4
glucose metabolism
antiviral immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.728082/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.728082/full

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