The G2A Receptor Deficiency Aggravates Atherosclerosis in Rats by Regulating Macrophages and Lipid Metabolism

The G2A Receptor Deficiency Aggravates Atherosclerosis in Rats by Regulating Macrophages and Lipid Metabolism

The orphan G protein-coupled receptor G2A has been linked to atherosclerosis development. However, available data from mouse models are controversial. Rat G2A receptor bears more similarities with its human homolog. We proposed that the atherosclerosis model established from Ldlr–/– rat, which has b...

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Bibliographic Details
Main Authors: Xueqin Cui, Roumei Xing, Yue Tian, Man Wang, Yue Sun, Yongqian Xu, Yiqing Yang, Yongliang Zhao, Ling Xie, Yufang Xiao, Dali Li, Biao Zheng, Mingyao Liu, Huaqing Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Physiology
Subjects:
G2A
atherosclerosis
LDLR deficient rat
lipid disorder
macrophage
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.659211/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.659211/full

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