Long non-coding RNA AFAP1-AS1 accelerates lung cancer cells migration and invasion by interacting with SNIP1 to upregulate c-Myc

Abstract Actin filament associated protein 1 antisense RNA 1 (named AFAP1-AS1) is a long non-coding RNA and overexpressed in many cancers. This study aimed to identify the role and mechanism of AFAP1-AS1 in lung cancer. The AFAP1-AS1 expression was firstly assessed in 187 paraffin-embedded lung canc...

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Bibliographic Details
Main Authors: Yu Zhong, Liting Yang, Fang Xiong, Yi He, Yanyan Tang, Lei Shi, Songqing Fan, Zheng Li, Shanshan Zhang, Zhaojian Gong, Can Guo, Qianjin Liao, Yujuan Zhou, Ming Zhou, Bo Xiang, Xiaoling Li, Yong Li, Zhaoyang Zeng, Guiyuan Li, Wei Xiong
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00562-y