Drug-Induced Hepatotoxicity: Metabolic, Genetic and Immunological Basis

Drug-induced hepatotoxicity is a significant cause of acute liver failure and is usually the primary reason that therapeutic drugs are removed from the commercial market. Multiple mechanisms can culminate in drug hepatotoxicity. Metabolism, genetics and immunology separately and in concert play dist...

Full description

Bibliographic Details
Main Author: Dolores B. Njoku
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/15/4/6990