Drug-Induced Hepatotoxicity: Metabolic, Genetic and Immunological Basis
Drug-induced hepatotoxicity is a significant cause of acute liver failure and is usually the primary reason that therapeutic drugs are removed from the commercial market. Multiple mechanisms can culminate in drug hepatotoxicity. Metabolism, genetics and immunology separately and in concert play dist...
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Format: | Article |
Language: | English |
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MDPI AG
2014-04-01
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Series: | International Journal of Molecular Sciences |
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Online Access: | http://www.mdpi.com/1422-0067/15/4/6990 |