Disentangling astroglial physiology with a realistic cell model in silico

Astrocytes have gained increasing attention for their roles in regulating neural circuits via neurotransmitter uptake, K + buffering, and ability to signal via Ca2 + transients. Here, the authors develop a computational modelling environment for astrocytes, akin to the NEURON environment, called AST...

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Bibliographic Details
Main Authors: Leonid P. Savtchenko, Lucie Bard, Thomas P. Jensen, James P. Reynolds, Igor Kraev, Nikolay Medvedev, Michael G. Stewart, Christian Henneberger, Dmitri A. Rusakov
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05896-w