Host adaptation in gut Firmicutes is associated with sporulation loss and altered transmission cycle

Host adaptation in gut Firmicutes is associated with sporulation loss and altered transmission cycle

Abstract Background Human-to-human transmission of symbiotic, anaerobic bacteria is a fundamental evolutionary adaptation essential for membership of the human gut microbiota. However, despite its importance, the genomic and biological adaptations underpinning symbiont transmission remain poorly und...

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Bibliographic Details
Main Authors: Hilary P. Browne, Alexandre Almeida, Nitin Kumar, Kevin Vervier, Anne T. Adoum, Elisa Viciani, Nicholas J. R. Dawson, Samuel C. Forster, Claire Cormie, David Goulding, Trevor D. Lawley
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Genome Biology
Subjects:
Sporulation
Intestinal microbiota
Microbiome
Metagenomics
Host adaptation
Genome reduction
Online Access:https://doi.org/10.1186/s13059-021-02428-6

Internet

https://doi.org/10.1186/s13059-021-02428-6

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