The Onchocerca volvulus cysteine proteinase inhibitor, Ov-CPI-2, is a target of protective antibody response that increases with age.

Despite considerable efforts, a suitable vaccine against Onchocerca volvulus infection has remained elusive. Herein, we report on the use of molecular tools to identify and characterize O. volvulus antigens that are possibly associated with the development of concomitant immunity in onchocerciasis.T...

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Bibliographic Details
Main Authors: Fidelis Cho-Ngwa, Jing Liu, Sara Lustigman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2927424?pdf=render