The genomes of precision edited cloned calves show no evidence for off-target events or increased de novo mutagenesis

Abstract Background Animal health and welfare are at the forefront of public concern and the agricultural sector is responding by prioritising the selection of welfare-relevant traits in their breeding schemes. In some cases, welfare-enhancing traits such as horn-status (i.e., polled) or diluted coa...

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Bibliographic Details
Main Authors: Swati Jivanji, Chad Harland, Sally Cole, Brigid Brophy, Dorian Garrick, Russell Snell, Mathew Littlejohn, Götz Laible
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Genomics
Online Access:https://doi.org/10.1186/s12864-021-07804-x