Inhibition of FGF and TGF-β Pathways in hESCs Identify STOX2 as a Novel SMAD2/4 Cofactor

The fibroblast growth factor (FGF) and the transforming growth factor-β (TGF-β) pathways are both involved in the maintenance of human embryonic stem cells (hESCs) and regulate the onset of their differentiation. Their converging functions have suggested that these pathways might share a wide range...

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Bibliographic Details
Main Authors: Peter F. Renz, Daniel Spies, Panagiota Tsikrika, Anton Wutz, Tobias A. Beyer, Constance Ciaudo
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/9/12/470