Mitochondrial Activity and Cyr1 Are Key Regulators of Ras1 Activation of C. albicans Virulence Pathways.

Candida albicans is both a major fungal pathogen and a member of the commensal human microflora. The morphological switch from yeast to hyphal growth is associated with disease and many environmental factors are known to influence the yeast-to-hyphae switch. The Ras1-Cyr1-PKA pathway is a major regu...

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Bibliographic Details
Main Authors: Nora Grahl, Elora G Demers, Allia K Lindsay, Colleen E Harty, Sven D Willger, Amy E Piispanen, Deborah A Hogan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4552728?pdf=render