Microsatellite instability in colorectal cancer and association with thymidylate synthase and dihydropyrimidine dehydrogenase expression

<p>Abstract</p> <p>Background</p> <p>Microsatellite instability (MSI) refers to mutations in short motifs of tandemly repeated nucleotides resulting from replication errors and deficient mismatch repair (MMR). Colorectal cancer with MSI has characteristic biology and ch...

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Bibliographic Details
Main Authors: Kruhøffer Mogens, Vainer Ben, Jensen Søren A, Sørensen Jens B
Format: Article
Language:English
Published: BMC 2009-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/25