A novel TEX11 mutation induces azoospermia: a case report of infertile brothers and literature review

A novel TEX11 mutation induces azoospermia: a case report of infertile brothers and literature review

Abstract Background Testis-expressed gene 11 (TEX11) is an X-linked gene and essential for meiotic recombination and chromosomal synapsis. TEX11 deficiency causes meiotic arrest and male infertility, and many TEX11 mutations have been found in azoospermic and infertile men. Case presentation This st...

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Bibliographic Details
Main Authors: Yanwei Sha, Liangkai Zheng, Zhiyong Ji, Libin Mei, Lu Ding, Shaobin Lin, Xu Wang, Xiaoyu Yang, Ping Li
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Medical Genetics
Subjects:
TEX11 mutation
Azoospermia
Infertility
Meiosis
Whole-exome sequencing
Online Access:http://link.springer.com/article/10.1186/s12881-018-0570-4

Internet

http://link.springer.com/article/10.1186/s12881-018-0570-4

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