Functional and clinical significance of ROR1 in lung adenocarcinoma

Functional and clinical significance of ROR1 in lung adenocarcinoma

Abstract Background Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is normally detectable in embryonic tissues and absent in adult tissues. ROR1 was shown to inhibit apoptosis, potentiate EGFR signaling and reported to be overexpressed and associated with poor prognosis in several tumor mode...

Full description

Bibliographic Details
Main Authors: Schiavone Giovanna, Epistolio Samantha, Martin Vittoria, Molinari Francesca, Barizzi Jessica, Mazzucchelli Luca, Frattini Milo, Wannesson Luciano
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Cancer
Subjects:
Non-small cell lung cancer
ROR1
Targeted therapies
Overall survival
EGFR
Online Access:http://link.springer.com/article/10.1186/s12885-020-07587-6

Internet

http://link.springer.com/article/10.1186/s12885-020-07587-6

Similar Items