Current data on IL-17 and Th17 cells and implications for graft versus host disease

Human interleukin 17 was first described in 1995 as a new cytokine produced primarily by activated T CD4+ cells that stimulate the secretion of IL-6 and IL-8 by human fibroblasts, besides increasing the expression of ICAM-1. Various authors have reported that IL-17A has a role in the protection of o...

Full description

Bibliographic Details
Main Authors: Marília Normanton, Luciana Cavalheiro Marti
Format: Article
Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein
Series:Einstein (São Paulo)
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082013000200019&lng=en&tlng=en