HDAC inhibitor valproic acid protects heart function through Foxm1 pathway after acute myocardial infarctionResearch in context

HDAC inhibitor valproic acid protects heart function through Foxm1 pathway after acute myocardial infarctionResearch in context

Background: Epigenetic histone acetylation is a major event controlling cell functions, such as metabolism, differentiation and repair. Here, we aim to determine whether Valproic acid (VPA), a FDA approved inhibitor of histone deacetylation for bipolar disease, could protect heart against myocardial...

Full description

Bibliographic Details
Main Authors: Shuo Tian, Ienglam Lei, Wenbin Gao, Liu Liu, Yijing Guo, Jeffery Creech, Todd J. Herron, Shaoxiang Xian, Peter X. Ma, Y. Eugene Chen, Yongqing Li, Hasan B. Alam, Zhong Wang
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418305747

Internet

http://www.sciencedirect.com/science/article/pii/S2352396418305747

Similar Items