Protein-bound 4-hydroxy-2-hexenal as a marker of oxidized n-3 polyunsaturated fatty acids

Protein-bound 4-hydroxy-2-hexenal as a marker of oxidized n-3 polyunsaturated fatty acids

In the present study, to investigate the contribution of n-3 PUFAs in the oxidative modification of protein in vivo, we characterize the covalent binding of 4-hydroxy-2-hexenal (HHE), a potent cytotoxic aldehyde originating from the peroxidation of n-3 PUFAs, to protein and describe the production o...

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Bibliographic Details
Main Authors: Satoshi Yamada, Tadashi Funada, Noriyuki Shibata, Makio Kobayashi, Yoshichika Kawai, Emi Tatsuda, Atsunori Furuhata, Koji Uchida
Format: Article
Language:English
Published: Elsevier 2004-04-01
Series:Journal of Lipid Research
Subjects:
reactive aldehydes
oxidatively modified proteins
oxidized low density lipoprotein
atherosclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520318460

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http://www.sciencedirect.com/science/article/pii/S0022227520318460

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