Morphogenesis and cytopathic effect of SARS-CoV-2 infection in human airway epithelial cells

Morphogenesis and cytopathic effect of SARS-CoV-2 infection in human airway epithelial cells

Here, the authors characterize replication of SARS-CoV-2 in human airway epithelial (HAE) cultures and show that it can infect ciliated and secretory cells, affects transepithelial electrical resistance and causes plaque-like cytopathic effects associated with apoptosis.

Bibliographic Details
Main Authors: Na Zhu, Wenling Wang, Zhidong Liu, Chaoyang Liang, Wen Wang, Fei Ye, Baoying Huang, Li Zhao, Huijuan Wang, Weimin Zhou, Yao Deng, Longfei Mao, Chongyu Su, Guangliang Qiang, Taijiao Jiang, Jincun Zhao, Guizhen Wu, Jingdong Song, Wenjie Tan
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17796-z

Internet

https://doi.org/10.1038/s41467-020-17796-z

Similar Items