Untangling Extracellular Proteasome-Osteopontin Circuit Dynamics in Multiple Sclerosis

Untangling Extracellular Proteasome-Osteopontin Circuit Dynamics in Multiple Sclerosis

The function of proteasomes in extracellular space is still largely unknown. The extracellular proteasome-osteopontin circuit has recently been hypothesized to be part of the inflammatory machinery regulating relapse/remission phase alternation in multiple sclerosis. However, it is still unclear wha...

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Bibliographic Details
Main Authors: Chiara Dianzani, Domizia Vecchio, Nausicaa Clemente, Annalisa Chiocchetti, Filippo Martinelli Boneschi, Daniela Galimberti, Umberto Dianzani, Cristoforo Comi, Michele Mishto, Juliane Liepe
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
immunoproteasome
chemotaxis
computational modelling
system biology
Online Access:https://www.mdpi.com/2073-4409/8/3/262

Internet

https://www.mdpi.com/2073-4409/8/3/262

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