Ketone Bodies Inhibit the Opening of Acid-Sensing Ion Channels (ASICs) in Rat Hippocampal Excitatory Neurons in vitro

Ketone Bodies Inhibit the Opening of Acid-Sensing Ion Channels (ASICs) in Rat Hippocampal Excitatory Neurons in vitro

Objectives: Despite the long-term efficacy of antiepileptic drug treatments, frequent attacks of drug-resistant epilepsy necessitate the development of new antiepileptic drug therapy targets. The ketogenic diet is a high-fat, low-carbohydrate diet that has been shown to be effective in treating drug...

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Bibliographic Details
Main Authors: Fei Zhu, Wei Shan, Qinlan Xu, Anchen Guo, Jianping Wu, Qun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Neurology
Subjects:
ketone body
ketogenic diet
acid-sensing ion channels
patch clamp
neuron
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00155/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.00155/full

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