Effects of Minocycline on Urine Albumin, Interleukin-6, and Osteoprotegerin in Patients with Diabetic Nephropathy: A Randomized Controlled Pilot Trial.

BACKGROUND:We tested minocycline as an anti-proteinuric adjunct to renin-angiotensin-aldosterone system inhibitors (RAASi) in diabetic nephropathy (DN) and measured urinary biomarkers to evaluate minocycline's biological effects. METHODS: DESIGN:Prospective, single center, randomized, placebo-c...

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Bibliographic Details
Main Authors: Anuja P Shah, Jenny I Shen, Ying Wang, Lili Tong, Youngju Pak, Ali Andalibi, Janine A LaPage, Sharon G Adler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4809491?pdf=render