NLRP3 Inflammasome and Its Critical Role in Gynecological Disorders and Obstetrical Complications

Inflammasomes, intracellular, multimeric protein complexes, are assembled when damage signals stimulate nucleotide-binding oligomerization domain receptors (NLRs). Several inflammasomes have been reported, including the NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3), NLRP1, NLRP7, ice prot...

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Bibliographic Details
Main Authors: Xuhui Fang, Yanshi Wang, Yu Zhang, Yelin Li, Joanne Kwak-kim, Li Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.555826/full