Identification of the NADP<sup>+</sup> Structural Binding Site and Coenzyme Effect on the Fused G6PD::6PGL Protein from <i>Giardia lamblia</i>

<i>Giardia lambia</i> is a flagellated protozoan parasite that lives in the small intestine and is the causal agent of giardiasis. It has been reported that <i>G. lamblia</i> exhibits glucose-6-phosphate dehydrogenase (G6PD), the first enzyme in the pentose phosphate pathway...

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Main Authors: Laura Morales-Luna, Abigail González-Valdez, Yudibeth Sixto-López, José Correa-Basurto, Beatriz Hernández-Ochoa, Noemí Cárdenas-Rodríguez, Rosa Angélica Castillo-Rodríguez, Daniel Ortega-Cuellar, Roberto Arreguin-Espinosa, Verónica Pérez de la Cruz, Hugo Serrano-Posada, Sara Centeno-Leija, Luz María Rocha-Ramírez, Edgar Sierra-Palacios, Alba Mónica Montiel-González, Yadira Rufino-González, Jaime Marcial-Quino, Saúl Gómez-Manzo
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/1/46