Long-Term Suppression of c-Jun and nNOS Preserves Ultrastructural Features of Lower Motor Neurons and Forelimb Function after Brachial Plexus Roots Avulsion

Long-Term Suppression of c-Jun and nNOS Preserves Ultrastructural Features of Lower Motor Neurons and Forelimb Function after Brachial Plexus Roots Avulsion

Brachial plexus root avulsions cause debilitating upper limb paralysis. Short-term neuroprotective treatments have reported preservation of motor neurons and function in model animals while reports of long-term benefits of such treatments are scarce, especially the morphological sequelae. This morph...

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Bibliographic Details
Main Authors: Prince Last Mudenda Zilundu, Xiaoying Xu, Zaara Liaquat, Yaqiong Wang, Ke Zhong, Rao Fu, Lihua Zhou
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
motor neuron ultrastructure
ventral horn
brachial plexus roots avulsion
neuroprotection
motor function
Online Access:https://www.mdpi.com/2073-4409/10/7/1614

Internet

https://www.mdpi.com/2073-4409/10/7/1614

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