Mosquito-bite infection of humanized mice with chikungunya virus produces systemic disease with long-term effects.

Chikungunya virus (CHIKV) is an emerging, mosquito-borne alphavirus responsible for acute to chronic arthralgias and neuropathies. Although it originated in central Africa, recent reports of disease have come from many parts of the world, including the Americas. While limiting human CHIKV cases thro...

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Bibliographic Details
Main Authors: Brianne M Hibl, Natalie J M Dailey Garnes, Alexander R Kneubehl, Megan B Vogt, Jennifer L Spencer Clinton, Rebecca R Rico-Hesse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009427