Dysregulation of Neuronal Genes by Fetal-Neonatal Iron Deficiency Anemia Is Associated with Altered DNA Methylation in the Rat Hippocampus

Early-life iron deficiency results in long-term abnormalities in cognitive function and affective behavior in adulthood. In preclinical models, these effects have been associated with long-term dysregulation of key neuronal genes. While limited evidence suggests histone methylation as an epigenetic...

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Bibliographic Details
Main Authors: Yu-Chin Lien, David E Condon, Michael K Georgieff, Rebecca A Simmons, Phu V Tran
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/11/5/1191