Temporal analysis of meiotic DNA double-strand break formation and repair in Drosophila females.

Using an antibody against the phosphorylated form of His2Av (gamma-His2Av), we have described the time course for the series of events leading from the formation of a double-strand break (DSB) to a crossover in Drosophila female meiotic prophase. MEI-P22 is required for DSB formation and localizes t...

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Bibliographic Details
Main Authors: S Mehrotra, K S McKim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1657055?pdf=render