Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

Systemic lupus erythematosus (SLE) is a clinically heterogeneous, systemic autoimmune disease characterized by autoantibody formation. Previously published genome-wide association studies (GWAS) have investigated SLE as a single phenotype. Therefore, we conducted a GWAS to identify genetic factors a...

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Bibliographic Details
Main Authors: Sharon A Chung, Kimberly E Taylor, Robert R Graham, Joanne Nititham, Annette T Lee, Ward A Ortmann, Chaim O Jacob, Marta E Alarcón-Riquelme, Betty P Tsao, John B Harley, Patrick M Gaffney, Kathy L Moser, SLEGEN, Michelle Petri, F Yesim Demirci, M Ilyas Kamboh, Susan Manzi, Peter K Gregersen, Carl D Langefeld, Timothy W Behrens, Lindsey A Criswell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3048371?pdf=render