Strong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removal.

Strong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removal.

In utero transmission of HIV-1 occurs on average in only 3%-15% of HIV-1-exposed neonates born to mothers not on antiretroviral drug therapy. Thus, despite potential exposure, the majority of infants remain uninfected. Weak HIV-1-specific T-cell responses have been detected in children exposed to HI...

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Bibliographic Details
Main Authors: Fatema A Legrand, Douglas F Nixon, Christopher P Loo, Erika Ono, Joan M Chapman, Maristela Miyamoto, Ricardo S Diaz, Amélia M N Santos, Regina C M Succi, Jacob Abadi, Michael G Rosenberg, Maria Isabel de Moraes-Pinto, Esper G Kallas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1762312?pdf=render

Internet

http://europepmc.org/articles/PMC1762312?pdf=render

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