Thioctic Acid Derivatives as Building Blocks to Incorporate DNA Oligonucleotides onto Gold Nanoparticles

Thioctic Acid Derivatives as Building Blocks to Incorporate DNA Oligonucleotides onto Gold Nanoparticles

Oligonucleotide gold nanoparticle conjugates are being used as diagnostic tools and gene silencing experiments. Thiol-chemistry is mostly used to functionalize gold nanoparticles with oligonucleotides and to incorporate DNA or RNA molecules onto gold surfaces. However, the stability of such nucleic...

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Bibliographic Details
Main Authors: Sónia Pérez-Rentero, Santiago Grijalvo, Guillem Peñuelas, Carme Fàbrega, Ramon Eritja
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Molecules
Subjects:
thioctic acid
threoninol
DNA
DNA-gold nanoparticle conjugates
stability
surface coverage
cathepsin
Online Access:http://www.mdpi.com/1420-3049/19/7/10495

Internet

http://www.mdpi.com/1420-3049/19/7/10495

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