Effects of Polygonum multiflorum extract on DNA methylation and gene transcription in brain tissue of aging mice

Objective To determine the effect of Polygonum multiflorum extract (PME) on DNA methylation and transcriptome levels in the brain tissue of D-galactose-induced senescence C57BL/6 mice, and explore its mechanism of delaying aging. Methods Fifty C57BL/6 mice were randomly divided into 5 groups, that i...

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Bibliographic Details
Main Authors: ZOU Jiayi, YANG Jiangquan, XU Lin, FAN Fang, GE Zhenglong
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2020-01-01
Series:Di-san junyi daxue xuebao
Subjects:
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/201908210.htm