A Genetic Score Associates With Pioglitazone Response in Patients With Non-alcoholic Steatohepatitis

A Genetic Score Associates With Pioglitazone Response in Patients With Non-alcoholic Steatohepatitis

Pioglitazone is used effectively to treat non-alcoholic steatohepatitis (NASH), but there is marked variability in response. This study examined whether genetic variation contributes to pioglitazone response variability in patients with NASH. This genetic substudy includes 55 participants of a rando...

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Bibliographic Details
Main Authors: Marina Kawaguchi-Suzuki, Kenneth Cusi, Fernando Bril, Yan Gong, Taimour Langaee, Reginald F. Frye
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Pharmacology
Subjects:
NAFLD
fatty liver
NASH
thiazolidinediones
pharmacogenetics
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00752/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00752/full

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