Targeted inactivation of Salmonella Agona metabolic genes by group II introns and in vivo assessment of pathogenicity and anti-tumour activity in mouse model

The fight against cancer has been a never-ending battle. Limitations of conventional therapies include lack of selectivity, poor penetration and highly toxic to the host. Using genetically modified bacteria as a tumour therapy agent has gained the interest of scientist from the past few decades. Low...

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Bibliographic Details
Main Authors: Chin Piaw Gwee, Chai Hoon Khoo, Swee Keong Yeap, Geok Chin Tan, Yoke Kqueen Cheah
Format: Article
Language:English
Published: PeerJ Inc. 2019-01-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/5989.pdf