High tidal volume mechanical ventilation-induced lung injury in rats is greater after acid instillation than after sepsis-induced acute lung injury, but does not increase systemic inflammation: an experimental study

<p>Abstract</p> <p>Background</p> <p>To examine whether acute lung injury from direct and indirect origins differ in susceptibility to ventilator-induced lung injury (VILI) and resultant systemic inflammatory responses.</p> <p>Methods</p> <p>Rats...

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Bibliographic Details
Main Authors: Kuiper Jan, Plötz Frans B, Groeneveld AB Johan, Haitsma Jack J, Jothy Serge, Vaschetto Rosanna, Zhang Haibo, Slutsky Arthur S
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Anesthesiology
Subjects:
Online Access:http://www.biomedcentral.com/1471-2253/11/26