Tubeimoside I Antagonizes Yoda1-Evoked Piezo1 Channel Activation

Piezo1, a mechanosensitive Ca2+-permeable non-selective cationic ion channel protein, is involved in a wide range of biological processes and plays crucial roles in vascular development. However, the pharmacology of this protein is in its infancy. Yoda1, the first specific chemical activator of Piez...

Full description

Bibliographic Details
Main Authors: Silin Liu, Xianmei Pan, Wenbin Cheng, Bo Deng, Yu He, Lei Zhang, Yile Ning, Jing Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00768/full