Mitochondrial allostatic load? The combined effect of glucose intolerance and mitochondrial DNA mutations on the incidence of neurological symptoms

Rationale/statement of the problem : High blood glucose levels increase individuals’ susceptibility to age-related diseases and mortality. However, the molecular mechanisms by which hyperglycemia impairs cellular function is unclear. Emerging research suggests that mitochondrial dysfuncti...

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Bibliographic Details
Main Authors: Dhom Martin Picard, Nichola Lax, Thiloka Ratnaike, Robert-Paul Juster, Douglass M. Turnbull
Format: Article
Language:English
Published: Taylor & Francis Group 2012-09-01
Series:European Journal of Psychotraumatology
Subjects: