Gene disruption of the DNA topoisomerase IB small subunit induces a non-viable phenotype in the hemoflagellate <it>Leishmania major</it>
<p>Abstract</p> <p>Background</p> <p>The unusual heterodimeric leishmanial DNA topoisomerase IB consists of a large subunit containing the phylogenetically conserved "core" domain, and a small subunit harboring the C-terminal region with the characteristic tyr...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-07-01
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Series: | BMC Microbiology |
Online Access: | http://www.biomedcentral.com/1471-2180/8/113 |