Probiotic Lactobacilli Isolated from Kefir Promote Down-Regulation of Inflammatory Lamina Propria T Cells from Patients with Active IBD

Probiotic Lactobacilli Isolated from Kefir Promote Down-Regulation of Inflammatory Lamina Propria T Cells from Patients with Active IBD

Ulcerative colitis and Crohn’s disease, the two main forms of inflammatory bowel disease (IBD), are immunologically mediated disorders. Several therapies are focused on activated T cells as key targets. Although Lactobacillus kefiri has shown anti-inflammatory effects in animal models, few studies w...

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Bibliographic Details
Main Authors: Renata Curciarello, Karina E. Canziani, Ileana Salto, Emanuel Barbiera Romero, Andrés Rocca, Ivan Doldan, Emmanuel Peton, Santiago Brayer, Alicia M. Sambuelli, Silvina Goncalves, Pablo Tirado, Gustavo J. Correa, Martín Yantorno, Laura Garbi, Guillermo H. Docena, María de los Ángeles Serradell, Cecilia I. Muglia
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
ulcerative colitis
Crohn’s disease
probiotics
immunomodulation
mucosal samples
Lactobacillus kefiri CIDCA 8348
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.658026/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.658026/full

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