DENV2 Pseudoviral Particles with Unprocessed Capsid Protein Are Assembled and Infectious

Proteolytic processing of flavivirus polyprotein is a uniquely controlled process. To date, the sequential cleavage of the capsid anchor sequence at the junction of C-PrM has been considered essential for the production of flaviviruses. In this study, we used two experimental approaches to show the...

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Bibliographic Details
Main Authors: Jyoti Rana, Oscar R. Burrone
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/1/27