Structural Insights in Mammalian Sialyltransferases and Fucosyltransferases: We Have Come a Long Way, but It Is Still a Long Way Down

Structural Insights in Mammalian Sialyltransferases and Fucosyltransferases: We Have Come a Long Way, but It Is Still a Long Way Down

Mammalian cell surfaces are modified with complex arrays of glycans that play major roles in health and disease. Abnormal glycosylation is a hallmark of cancer; terminal sialic acid and fucose in particular have high levels in tumor cells, with positive implications for malignancy. Increased sialyla...

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Bibliographic Details
Main Authors: Ravneet Kaur Grewal, Abdul Rajjak Shaikh, Suresh Gorle, Manjeet Kaur, Paula Alexendra Videira, Luigi Cavallo, Mohit Chawla
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Molecules
Subjects:
sialyltransferase
fucosyltransferase
glyocosyltransferases in cancer
drug design
Online Access:https://www.mdpi.com/1420-3049/26/17/5203

Internet

https://www.mdpi.com/1420-3049/26/17/5203

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