A role for locus coeruleus in Parkinson tremor

We analyzed rest tremor, one of the aetiologically most elusive hallmarks of Parkinson disease (PD), in 12 consecutive PD patients during a specific task activating the locus coeruleus (LC) to investigate a putative role of noradrenaline (NA) in tremor generation and suppression. Clinical diagnosis...

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Main Authors: Ioannis Ugo eIsaias, Alberto eMarzegan, Gianni ePezzoli, Giorgio eMarotta, Margherita eCanesi, Jens eVolkmann, Gabriele E.M. Biella, Paolo eCavallari
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-01-01
Series:Frontiers in Human Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnhum.2011.00179/full