Single cell RNA-seq data and bulk gene profiles reveal a novel signature of disease progression in multiple myeloma

Single cell RNA-seq data and bulk gene profiles reveal a novel signature of disease progression in multiple myeloma

Abstract Background The development of multiple myeloma (MM) is considered to involve a multistep transformation process, but the role of cytogenetic abnormalities and molecular alterations in determining the cell fate of multiple myeloma (MM) remains unclear. Here, we have analyzed single cell RNA-...

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Bibliographic Details
Main Authors: Zhiyong Zeng, Junfang Lin, Kejie Zhang, Xizhe Guo, Xiaoqiang Zheng, Apeng Yang, Junmin Chen
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Cancer Cell International
Subjects:
Single cell RNA-seq
Bulk gene profiles
Novel signature
Disease progression
Multiple myeloma
Online Access:https://doi.org/10.1186/s12935-021-02190-6

Internet

https://doi.org/10.1186/s12935-021-02190-6

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