Identification of binding pockets in protein structures using a knowledge-based potential derived from local structural similarities
<p>Abstract</p> <p>Background</p> <p>The identification of ligand binding sites is a key task in the annotation of proteins with known structure but uncharacterized function. Here we describe a knowledge-based method exploiting the observation that unrelated binding sit...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-03-01
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Series: | BMC Bioinformatics |